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o cell death by oxidative pressure by means of enhanced GSH efflux also prevents intracellular GSSG accumulation. Therefore the cell death observed in MRP1 overexpressing cells is often attributed to accumulation of ROS from GSH depletion. Having said that, in one more study intracellular GSH levels weren't depleted in MRP1-overexpressing HEK293 cells treated with staurosporine/ Fas antibody desp

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